Acetonitrile
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Acetonitrile (which is also known as methyl cyanide, by its IUPAC name) is a colorless liquid with a sweet, ether-like odor. It is a simple organic compound with a linear structure consisting of carbon, hydrogen, and nitrogen atoms. The chemical formula for acetonitrile is CH₃CN. The molecular structure of acetonitrile involves a linear arrangement of carbon, hydrogen, and nitrogen atoms with a triple bond between carbon and nitrogen, as shown in the figure below.
Acrylonitrile is an organic compound with the molecular formula CH2CHCN. It is a colorless, volatile, flammable liquid. It has a pungent odor of garlic or onions. It is also known as vinyl cyanide and cyanoethylene.
Acrylonitrile is used to make acrylic and modified acrylic fibers for use in clothing and textiles such as wool pullovers, sportswear, carpets, and upholstery. Acrylic fibers are also used as a precursor for carbon fiber production. It is used to produce plastics and resins such as acrylonitrile-butadiene-styrene (ABS), styrene-acrylonitrile (SAN), and nitrile rubber for fuel hoses and O-ring seals. Acrylonitrile is also used as a chemical intermediate in the production of other chemicals such as acrylamide and adiponitrile.
Shandong Qilu Petrochemical Qitai Petrochemical Co., Ltd. is one of the subsidiaries of Kaitai. At present, acrylonitrile is mainly exported to Brazil, Thailand, and some other South American countries.
Solvent
Pharmaceutical manufacturers commonly use acetonitrile as a solvent predominantly. They mold and cast plastic materials using this, they spin fibers with acetonitrile, and they use it for extracting fatty acids from vegetable oils and animals and also in lithium batteries.
Acetonitrile is also an essential substance for chemical laboratories that use to detect a variety of materials, including pesticide residues.
Extractive distillation
The petrochemical industry uses acetonitrile in extractive distillation. Organic compound and acetonitrile have selective miscibility and this is why it is a popular choice for the particular industry niche. They use it to separate C4-hydrocarbons and olefin-diolefin mixtures.
Acetonitrile is completely miscible in water and can also blend well with carbon tetrachloride, chloroform, acetone, ether, ethanol and even ethylene chloride
Starting materials
Many choose acetonitrile as a starting material for synthesizing a variety of chemicals. These include:
• Acetomidine
• Thiamine
• Alpha-naphthyl acetic acid
• Acetophenone
Removing solution
You may also use acetonitrile for removing phenols, coloring matters and tars from petroleum hydrocarbons. Acetonitrile and the mentioned elements are not soluble.
Laboratory solvent
Laboratories also commonly use acetonitrile as a solvent for crystallizing a wide variety of chemicals. You will also see this substance actively in use HPLC analysis as a solvent.
Chemical Properties of Acetonitrile
Acetonitrile is very soluble in water. It mixes with most organic solvents, e.g. alcohols, esters, acetone, ether, benzene, chloroform, carbon tetrachloride and many unsaturated hydrocarbons. Acetonitrile does not mix with petroleum ether and many saturated hydrocarbons. Acetonitrile is incompatible with water, acids, bases, oleum, perchlorates, nitrating agents, reducing agents and alkali metals. Acetonitrile decomposes on contact with acids, water and steam, producing toxic fumes and flammable vapour. Acetonitrile reacts with strong oxidants such as nitric acid, chromic acid and sodium peroxide, causing fire and explosion hazards. Acetonitrile forms toxic fumes of hydrogen cyanide and nitrogen oxides on combustion. It attacks some forms of plastics, rubber and coatings.
Exposure to acetonitrile can be injurious to health and it usually occurs in the industries that actively engage in using or producing this substance. However, there are also high chances of the general population facing exposure to this chemical by consuming contaminated water, by breathing in the chemical and by eye or skin contact in its liquid or vapor form.
As precaution, one must refrain from staying in the area where acetonitrile is present in the atmosphere and move to a place where there's fresh air. In case of disrupted breathing, one may need artificial respiration.
In case of skin and eye protection, you must wear PPE, Nitrile Gloves and protective gear when working with acetonitrile. If you still happen to come into contact, you must wash your skin with large amounts of water and soap.
Discard any clothing that has come in contact with this harmful substance.

Top Industrial Uses of Acetonitrile
Acetonitrile is a chemical compound with the formula CH3CN. It is a colorless liquid that is miscible with water and many organic solvents. Acetonitrile has a variety of industrial uses, including:
Solvent: Acetonitrile is widely used as a solvent in chemical syntheses, extractions, and purifications. It is particularly useful for dissolving polar compounds and has a high solvent power for many organic compounds.
Chromatography: Acetonitrile is often used as an eluent (mobile phase) in chromatography, a technique used to separate and purify mixtures of chemicals. It is particularly useful in high-performance liquid chromatography (HPLC) and gas chromatography (GC).
Reagent: Acetonitrile is used as a reagent in the synthesis of a wide range of chemicals, including pharmaceuticals, dyes, and plastics.
Analytical chemistry
Acetonitrile is used in a variety of analytical chemistry techniques, including nuclear magnetic resonance (NMR) spectroscopy, infrared (IR) spectroscopy, and mass spectrometry (MS).
Cleaning
Acetonitrile can be used to clean and degrease surfaces and equipment in a variety of industrial settings.
Pesticide production
Acetonitrile is used in the production of certain pesticides.
Xtracting oil
Acetonitrile is used in the extraction of oil from shale and other sources.
Application Fields of Acetonitrile
Chemical synthesis and pharmaceutical industry: Acetonitrile is an important organic intermediate, widely used in the synthesis of organic compounds, especially for the production of dyes, catalysts, surfactants and so on. In pharmaceutical industry, acetonitrile is often used as pharmaceutical intermediates for synthesizing various drug materials, and it is also the extraction solvent for many drugs. For example, acetonitrile can be used to synthesize vitamin B1, metronidazole, ethambutol, tretinoin and other drugs, as well as anticancer drugs, antiviral drugs and so on.
Electronic industry and metallurgical industry: Acetonitrile is widely used in the preparation and cleaning of electronic materials because of its good electrical properties. In metallurgical industry, acetonitrile can be used as important solvent, deoxidizer or reducing agent in casting, steel making, aluminum making and other processes.
Agriculture: Acetonitrile is also widely used in pesticide synthesis, it is the key raw material for the preparation of pyrethroid insecticides, ethoxime and other pesticide intermediates.
Analytical chemistry: Acetonitrile is widely used as solvent and analytical reagent in chromatography, spectral analysis and other fields because of its good solubility and chemical stability. It can be used for extraction, separation and determination of a variety of compounds, such as fatty acids, amino acids, sugar and so on.
Semiconductor cleaning: High purity Acetonitrile has excellent cleaning performance and can be used to clean grease, wax, fingerprints, corrosives and flux residues on silicon wafers. It is an important cleaning agent in semiconductor manufacturing process.
Other applications: Acetonitrile can also be used in the production process of petroleum processing, leather tanning, printing and dyeing industry, and can be used as raw material of organic synthesis, catalyst or component of transition metal complexing catalyst. Acetonitrile also has some applications in fabric dyeing and coating.
Preparation Method of Acetonitrile
Acetylene cyanide method is a commonly used method for the production of acetonitrile, in which acetonitrile is produced by reacting acetylene with sodium cyanide in the presence of acidic catalyst. The specific process involves adding acetylene and sodium cyanide solution to a mixed solution of ethanol, water and acetic acid in a certain proportion to form a reaction mixture. Subsequently, sodium chloride is added to increase the reaction rate and yield, and an appropriate amount of an acidic catalyst such as sulfuric acid is added to promote the reaction. After the reaction is completed, high purity acetonitrile products are obtained through distillation and purification.
Acrylonitrile hydrolysis is another common method to produce acetonitrile by hydrolyzing acrylonitrile under acidic condition to produce acetonitrile. The specific process involves continuously injecting acrylonitrile into an acidic solution and gradually adding water to hydrolyze acrylonitrile to form acetonitrile. The reaction speed and product purity are controlled by controlling the reaction temperature and pressure, and finally the high purity acetonitrile product is obtained through distillation and purification steps.
Ethanol oxidation method is to produce acetonitrile from ethanol as raw material, through the oxidation of ethanol to form acetaldehyde, and then the reaction of acetaldehyde with ammonia to form acetonitrile. The specific process includes adding ethanol into the reactor with catalyst for oxidation reaction to generate acetaldehyde, and then mixing the generated acetaldehyde with ammonia to generate acetonitrile by reaction in the presence of catalyst. Finally, a high-purity acetonitrile product is obtained through steps such as distillation and purification.
Acetaldehyde amine synthesis is a method for producing acetonitrile from acetaldehyde and amine compounds by reacting to generate acetaldehyde amine, and then generating acetonitrile from acetaldehyde amine by dehydration reaction. The specific process includes adding acetaldehyde and amine compounds to a reactor, carrying out an amination reaction in the presence of a catalyst to generate acetaldehyde amine, and then removing water from the acetaldehyde amine by a dehydration reaction to generate acetonitrile. Finally, a high-purity acetonitrile product is obtained through steps such as distillation and purification.
Kaitai Petrochemical was founded in July 2004. With the strong support of all sectors of society, it established a subsidiary in Gaoqing County in 2011 and officially put into production in October 2013. Since 2018, Kaitai has newly put into operation the 180000 tons high-end white oil project of its subsidiary. Kaitai Petrochemical has developed into a diversified chemical group company.
Shandong kaitai is located in beautiful Qi ancient capital- Zibo, which enjoys superior geographic position and convenient traffic- north to Huanghe River, east to Qingdao port, and south to the Jinan airport, Shandong Kaitai never ceases its effort to serve customers, and sold acrylic acid esters to most parts of China and overseas. Kaitai is a comprehensive enterprise integrating acrylic acid, acrylic ester and white oil production.
Shandong Kaitai Petrochemical adheres to the enterprise tenet of "pursuing high-quality development of the enterprise, rewarding shareholders, "Constantly improve the happiness index of employees and take the road of common prosperity", implements sunshine management, develops with customers, grows with employees. Fulfill social responsibility and build a respected enterprise; Fulfill economic responsibilities, build an enterprise with good benefits and prospects, make employees rich together, have higher income, better welfare, more status and dignity, create a happy place, live better and realize the dream of Kaitai.
Shadong Kaitai has more than 1000 employees, including 200 with medium and senior professional titles. Shandong Kaitai was qualified to be national "three systems" certified enterprise; Shandong acrylate Engineering Technology Research Center; High tech enterprises in Shandong Province; Shandong honest enterprise; "Kaitai" acrylic acid is a famous brand product in Shandong Province. In 2019, the comprehensive strength of Kaitai ranked 42nd among the top 100 enterprises in Zibo.

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